From CBS News:

“U.S. intelligence picked up signals of a radar being turned on, sources told CBS News. U.S. satellites also detected two surface-to-air missile launches, which happened shortly before the plane exploded.”
From CNN:

“The US increasingly believes that Iran mistakenly shot down a Ukrainian airliner on Tuesday, according to multiple US officials. The working theory is based on continuing analysis of data from satellites, radar and electronic data collected routinely by US military and intelligence.
The flight was downed following Iranian strikes on US forces in Iraq.
Iran’s Civil Aviation Organization head, Ali Abedzadeh, said it would not hand the flight data recorders to Boeing or the United States after they were found on Wednesday.”

From New York Times: New video of possible missile striking the doomed airliner.