Ryanair has launched its biggest Spanish domestic schedule with 70 routes (+40% vs. last summer) and up to 800 weekly flights across 21 airports in Spain. This includes a further nine newly announced routes and an additional 16 flights every week on existing routes, starting from July 1, 2021:
| New Routes | Additional Flights | |||
| Route | Weekly Flights | Route | Weekly Flights | |
| Alicante – Ibiza | 3 | Menorca – Valencia | 7 (+4) | |
| Alicante – Menorca | 3 | Malaga – Valencia | 3 (+1) | |
| Mallorca – Zaragoza | 3 | Mallorca – Valencia | 14 (+4) | |
| Menorca – Seville | 3 | Gran Canaria – Valencia | 3 (+1) | |
| Mallorca – Tenerife Norte | 2 | Seville – Valencia | 5 (+1) | |
| Malaga – Menorca | 2 | Malaga – Santiago | 6 (+1) | |
| Alicante – Lanzarote | 2 | Ibiza – Seville | 5 (+2) | |
| Mallorca – Santander | 2 | Lanzarote – Seville | 3 (+1) | |
| Fuerteventura – Valencia | 1 | Fuerteventura-Seville | 3 (+1) | |